The UMR1027 research unit entitled “Risks, Chronic Diseases and Disability” is jointly affiliated to both INSERM (the French National Institute for Health and Medical Research) and the University of Toulouse. The team involved in PRODEMOS is led by Prof. Sandrine Andrieu and will support the present study through the unique experience developed over the years in designing multi-domain intervention trials for the prevention of dementia, and previous work on determinants of adherence and non-response and validation of outcome measures. The team works in close collaboration with the Toulouse University Hosptial, notably the Clinical Research Methodology Unit, and the Toulouse Gerontopole (headed by Professor Bruno Vellas), and results from their research activities are highly clinically-oriented, allowing their easy and direct implementation into daily clinical practice and, in general, to public health.

Sandrine Andrieu (M.D, PhD) is a Professor of Epidemiology and Public Health at the Toulouse University School of Medicine and the current president of the French Society for Geriatrics and Gerontology. She has been the head of the INSERM – Toulouse University UMR1027 research Unit on “Risks, Chronic Diseases and Disability” and of the “Ageing and Alzheimer Disease” research team within the unit since 2011. She is also head of Toulouse University Hospital’s Clinical Research Methodology Unit, and is responsible for methodological aspects of trials in the field of aging. She has published more than 220 international papers and book chapters on aging, and has been involved in numerous large intervention trials, including the PLASA, GuidAge, MAPT and HATICE studies, as well as large cohort studies of Alzheimer Disease patients (ICTUS, She is currently supervising 4 PhD students. In PRODEMOS, she is work package leader for WP2.