PRODEMOS publications

Eggink E, Hafdi M, Hoevenaar-Blom MP, Song M, Andrieu S, Barnes LE, Birck C, Brooks RL, Coley N, Ford E, Georges J, van der Groep A, van Gool WA, Handels R, Hou H, Li D, Liu H, Lyu J, van Marwijk H, van der Meijden M, Niu Y, Sadhwani S, Wang W, Wang Y, Wimo A, Ye X, Yu Y, Zeng Q, Zhang W, Wang W, Brayne C, Moll van Charante EP, Richard E. Prevention of dementia using mobile phone applications (PRODEMOS): protocol for an international randomised controlled trial. BMJ Open. 2021 Jun 9;11(6):e049762. doi: 10.1136/bmjopen-2021-049762.

Coley N, Andre L, Hoevenaar-Blom MP, Ngandu T, Beishuizen C, Barbera M, van Wanrooij L, Kivipelto M, Soininen H, van Gool W, Brayne C, Moll van Charante E, Richard E, Andrieu S; HATICE study group; PRODEMOS study group. Factors Predicting Engagement of Older Adults With a Coach-Supported eHealth Intervention Promoting Lifestyle Change and Associations Between Engagement and Changes in Cardiovascular and Dementia Risk: Secondary Analysis of an 18-Month Multinational Randomized Controlled Trial. J Med Internet Res. 2022 May 9;24(5):e32006.

Andre L, Giulioli C, Piau A, Bongard V, Richard E, Moll Van Charante E, Coley N, Andrieu S, for the PRODEMOS consortium. Telephone and smartphone-based interventions for cognitive and cardio-metabolic health in middle-aged and older adults: a systematic review. Accepted for publication in Clinical Interventions in Aging.

Nicola Coley,  Marieke P. Hoevenaar‐Blom,  Jan‐Willem van Dalen,  Eric P. Moll van Charante,  Miia Kivipelto,  Hilkka Soininen,  Sandrine Andrieu,  Edo Richard, on behalf of the  PRODEMOS consortium, the preDIVA study group, the MAPT/DSA group, and the HATICE consortium. Dementia risk scores as surrogate outcomes for lifestyle‐based multidomain prevention trials—rationale, preliminary evidence and challenges. Alzheimer’s Dement. 2020;1–12.

Hafdi M, Eggink E, Hoevenaar-Blom MP, Witvliet MP, Andrieu S, Barnes L, Brayne C, Brooks R, Coley N, Georges J, van der Groep A, van Marwijk H, van der Meijden M, Song L, Song M, Wang Y, Wang W, Wang W, Wimo A, Ye X, van Charante EPM, Richard E. Design and Development of a Mobile Health (mHealth) Platform for Dementia Prevention in the Prevention of Dementia by Mobile Phone Applications (PRODEMOS) Project. Front Neurol. 2021 Dec 16;12:733878. doi: 10.3389/fneur.2021.733878. eCollection 2021.

Eggink E, Hafdi M, Hoevenaar-Blom MP, et al. Attitudes and views on healthy lifestyle interventions for the prevention of dementia and cardiovascular disease among older people with low socioeconomic status: a qualitative study in the Netherlands. BMJ Open 2022;12:e055984

den Brok MGHE, Hoevenaar-Blom MP, Coley N, Andrieu S, van Dalen J, Meiller Y, Guillemont J, Brayne C, van Gool WA, Moll van Charante EP, Richard E. The Effect of Multidomain Interventions on Global Cognition, Symptoms of Depression and Apathy – A Pooled Analysis of Two Randomized Controlled Trials.  J Prev Alzheimers Dis. 2022;9(1):96-103. doi: 10.14283/jpad.2021.53.PMID: 35098979

Hafdi M, Hoevenaar-Blom MP, Richard E. Multi-domain interventions for the prevention of dementia and cognitive decline. Cochrane Database Syst Rev. 2021 Nov 8;11(11):CD013572.

Background publications

Edo Richard, Eric P Moll van Charante, Marieke P Hoevenaar-Blom, Nicola Coley, Mariagnese Barbera, Abraham van der Groep, Yannick Meiller, Francesca Mangialasche, Cathrien B Beishuizen, Susan Jongstra, Tessa van Middelaar, Lennard L Van Wanrooij, Tiia Ngandu, Juliette Guillemont, Sandrine Andrieu, Carol Brayne, Miia Kivipelto, Hilkka Soininen, Willem A Van Gool Healthy ageing through internet counselling in the elderly (HATICE): a multinational, randomised controlled trial Lancet Digit Health. 2019 Dec;1(8):e424-e434. doi: 10.1016/S2589-7500(19)30153-0. Epub 2019 Nov 14.

Andrieu S, Guyonnet S, Coley N, Cantet C, Bonnefoy M, Bordes S, Bories L, Cufi MN, Dantoine T, Dartigues JF, Desclaux F, Gabelle A, Gasnier Y, Pesce A, Sudres K, Touchon J, Robert P, Rouaud O, Legrand P, Payoux P, Caubere JP, Weiner M, Carrié I, Ousset PJ, Vellas B; MAPT Study Group. Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial. Lancet Neurol. 2017 Mar 27. pii: S1474-4422(17)30040-6. doi: 10.1016/S1474-4422(17)30040-6.

Moll van Charante EP, Richard E, Eurelings LS, van Dalen JW, Ligthart SA, van Bussel EF, Hoevenaar-Blom MP, Vermeulen M, van Gool WA. Effectiveness of a 6-year multidomain vascular care intervention to prevent dementia (preDIVA): a cluster-randomised controlled trial. Lancet. 2016 Aug 20;388(10046):797-805. doi: 10.1016/S0140-6736(16)30950-3. Epub 2016 Jul 26.

Edo Richard, Susan Jongstra, Hilkka Soininen, Carol Brayne, Eric P. Moll van Charante, Yannick Meiller, Bram van der Groep, Cathrien R. L. Beishuizen, Francesca Mangialasche, Mariagenese Barbera, Tiia Ngandu, Nicola Coley, Juliette Guillemont, Stéphanie Savy, Marcel G. W. Dijkgraaf, Ron J. G. Peters, Willem A. van Gool, Miia Kivipelto, Sandrine Andrieu. Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment. BMJ Open. 2016 Jun 10;6(6):e010806. doi: 10.1136/bmjopen-2015-010806.

Ngandu T, Lehtisalo J, Solomon A, Levälahti E, Ahtiluoto S, Antikainen R, Bäckman L, Hänninen T, Jula A, Laatikainen T, Lindström J, Mangialasche F, Paajanen T, Pajala S, Peltonen M, Rauramaa R, Stigsdotter-Neely A, Strandberg T, Tuomilehto J, Soininen H, Kivipelto M. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet. 2015 Mar 11. pii: S0140-6736(15)60461-5. doi: 10.1016/S0140-6736(15)60461-5